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Signaling Pathways

Signaling Pathways

A3724 PI-103 Hydrochloride

Target: PI3K|mTOR|DNA-PK

Summary: DNA-PK/PI 3-kinase/mTOR inhibitor

insoluble in H2O; insoluble in EtOH; ≥19.25 mg/mL
A3927 VS-5584 (SB2343)

Target: PI3K|mTOR

Summary: MTOR/P13K inhibitor,potent and selective

insoluble in H2O; ≥17.7 mg/mL
A8764 Rapalink-1

Target: mTOR

Summary: third-generation mTOR inhibitor

≥178.4 mg/mL
B1639 Ridaforolimus (Deforolimus, MK-8669)

Target: mTOR

Summary: MTOR inhibitor

≥49.5 mg/mL
B1641 WAY-600

Target: mTOR

Summary: MTOR inhibitor

≥12.38 mg/mL
A8169 Everolimus (RAD001)
8 Citation

Target: mTOR

Summary: MTOR inhibitor

≥47.91 mg/mL
A8488 NVP-BGT226

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor,selective and novel

insoluble in EtOH; insoluble in H2O; ≥16.28 mg/mL
A8499 PF-04691502

Target: Akt|PI3K|mTOR

Summary: PI3K/mTOR (FRAP) inhibitor

insoluble in H2O; insoluble in EtOH; ≥10.63 mg/mL
A8551 INK 128 (MLN0128)
4 Citation

Target: mTOR

Summary: MTOR(TORC-1/-2) inhibitor,potent and selective

insoluble in H2O; ≥15.45 mg/mL
A8556 GSK2126458
1 Citation

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor

≥25.3 mg/mL