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Signaling Pathways

Signaling Pathways

A3006 GDC-0068 (RG7440)

Target: Akt

Summary: Pan-AKT inhibitor,highly selective

≥22.9 mg/mL
A3010 MK-2206 dihydrochloride
21 Citation

Target: Akt

Summary: Akt1/2/3 inhibitor

insoluble in EtOH; ≥12.01 mg/mL
A3011 CHIR-99021 (CT99021)
2 Citation

Target: GSK-3

Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive

≥23.27 mg/mL
A3015 BKM120
1 Citation

Target: PI3K

Summary: Inhibitor of pan-Class I PI3K

≥20.52 mg/mL
A4097 CUDC-907

Target: Histone Deacetylases (HDACs)|PI3K

Summary: Potent PI3K/HDAC inhibitor

≥25.45 mg/mL
A3149 AKT inhibitor VIII
2 Citation

Target: Akt

Summary: Allosteric Akt kinase inhibitor

insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL
A3184 AR-A014418
2 Citation

Target: GSK-3

Summary: GSK3β inhibitor, ATP-competitive and selective

insoluble in EtOH; insoluble in H2O; ≥15.4 mg/mL
A3352 Daun02
2 Citation

Summary: Cell viability inhibitor,DNA synthisis inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.92 mg/mL
A3368 DMAT
2 Citation

Target: Pim|CK2|HIPK2|HIPK3

Summary: CK2 inhibitor,potent and selective

≥23.85 mg/mL
A3420 FMK

Target: Ribosomal s6 kinases (RSK)

Summary: RSK inhibitor

insoluble in H2O; ≥17.1 mg/mL