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Signaling Pathways

Signaling Pathways

A8346 BYL-719
1 Citation

Target: PI3K

Summary: Selective PI3Kα inhibitor

≥22.07 mg/mL
A8354 A66

Target: PI3K

Summary: P110α inhibitor

insoluble in H2O; ≥19.7 mg/mL
A8395 CHIR-98014

Target: GSK-3

Summary: GSK-3β inhibitor,selective and ATP-competitive

insoluble in H2O; insoluble in EtOH; ≥8.1 mg/mL
A8396 CHIR-99021 (CT99021) HCl

Target: GSK-3

Summary: GSK-3α/β inhibitor

≥25.1 mg/mL
A8551 INK 128 (MLN0128)
4 Citation

Target: mTOR

Summary: MTOR(TORC-1/-2) inhibitor,potent and selective

insoluble in H2O; ≥15.45 mg/mL
A8556 GSK2126458
1 Citation

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor

≥25.3 mg/mL
A8617 CCT128930 HCl

Target: Akt

Summary: AKT inhibitor

insoluble in H2O; ≥17.1 mg/mL
A8649 NU 7026

Target: PI3K|DNA-PK|ATM

Summary: DNPK inhibitor,ATP-competitive and potent

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
B3252 Dorsomorphin (Compound C)
5 Citation

Target: AMPK

Summary: AMPK inhibitor

insoluble in H2O; insoluble in EtOH; ≥8.49 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL