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Signaling Pathways

Signaling Pathways

A8250 LY 294002
16 Citation

Target: PI3K

Summary: Potent PI3K inhibitor
A5112 XL147

Target: PI3K

Summary: PI3K inhibitor,selective and reversible

≥22.45 mg/mL
A2681 TGX-221

Target: PI3K

Summary: PI3Kβ inhibitor,potent,selective and ATP competitive

insoluble in H2O; insoluble in EtOH; ≥68.7 mg/mL
A5176 AS-605240

Target: PI3K

Summary: Potent and selective PI 3-Kγ inhibitor

insoluble in H2O; insoluble in EtOH; ≥4.28 mg/mL
A8214 AZD8055
2 Citation

Target: mTOR

Summary: MTOR inhibitor

≥23.3 mg/mL
A1769 KU-0060648
1 Citation

Target: PI3K|DNA-PK

Summary: Dual DNA-PK/PI3-K inhibitor, ATP-competitive
A1720 Duvelisib (IPI-145, INK1197)

Target: PI3K

Summary: PI3K-δ/PI3K-γ inhibitor

≥20.84 mg/mL
A8312 Torin 1
7 Citation

Target: mTOR

Summary: MTOR inhibitor,potent and selective
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8318 PP242

Target: mTOR

Summary: MTOR inhibitor, selective and ATP-competitive