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Signaling Pathways

Signaling Pathways

B5853 MHY1485
2 Citation

Target: mTOR

Summary: mTOR activator, autophage inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.35 mg/mL
B6099 LY3023414

Target: Akt|PI3K|mTOR|DNA-PK

Summary: class I PI3K isoforms, mTOR and DNA-PK inhibitor

≥40.6 mg/mL
B1639 Ridaforolimus (Deforolimus, MK-8669)

Target: mTOR

Summary: MTOR inhibitor

≥49.5 mg/mL
B1641 WAY-600

Target: mTOR

Summary: MTOR inhibitor

≥12.38 mg/mL
A8167 Rapamycin (Sirolimus)
15 Citation

Target: mTOR

Summary: Original antifungal antibiotic

≥45.7 mg/mL
A8169 Everolimus (RAD001)
8 Citation

Target: mTOR

Summary: MTOR inhibitor

≥47.91 mg/mL
B1642 WYE-125132 (WYE-132)

Target: mTOR

Summary: ATP-competitive mTOR inhibitor, highly potent

insoluble in EtOH; insoluble in H2O; ≥13 mg/mL
B2172 PP121

Target: mTOR|Eph Receptors|VEGFR|PDGFR|Bcr-Abl|Src|DNA-PK|P110|Hck

Summary: Dual inhibitor of tyrosine and phosphoinositide kinases
B2176 GSK1059615

Target: PI3K|mTOR

Summary: PI3K and mTOR inhibitor,potent and reversible

insoluble in EtOH; insoluble in H2O; ≥8.33 mg/mL
B1640 Torin 2
1 Citation

Target: mTOR|DNA-PK|ATM/ATR

Summary: MTOR inhibitor,highly potent and selective

≥21.6 mg/mL