JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

Home
Signaling Pathways

Signaling Pathways

A5602 SB525334

Summary: (TGF-beta1) receptor inhibitor

≥34.3 mg/mL
A8324 LDN-193189

Target: BMP and Other Activin Receptors

Summary: ALK inhibitor,potent and selective

insoluble in DMSO; insoluble in EtOH; insoluble in H2O
A8393 CH5424802

Target: ALK

Summary: ALK inhibitor,potent and ATP-competitive
A8620 AZD-3463
3 Citation

Target: ALK|Insulin-like growth factors (IGFs)

Summary: ALK/IGF1R inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
B4882 PF-06463922

Target: ALK|ROS1

Summary: ALK/ROS1 inhibitor,potent and selective

insoluble in H2O; ≥20.3 mg/mL
B5859 Entrectinib

Target: Trk Receptors|ALK|ROS1

Summary: Orally active inhibitor of ALK kinase

≥28.05 mg/mL
B3686 DMH-1

Target: BMP and Other Activin Receptors

Summary: Selective BMP ALK2 receptor

insoluble in H2O; insoluble in EtOH; ≥9.51 mg/mL
B3688 ML347

Target: BMP and Other Activin Receptors

Summary: BMP receptor inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥5.87 mg/mL
A3020 (R)-Crizotinib
2 Citation

Target: c-MET

Summary: C-MET/ALK inhibitor,potent and ATP-competitve

insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL