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Signaling Pathways

Signaling Pathways

A8393 CH5424802

Target: ALK

Summary: ALK inhibitor,potent and ATP-competitive
A8620 AZD-3463
3 Citation

Target: ALK|Insulin-like growth factors (IGFs)

Summary: ALK/IGF1R inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
B4882 PF-06463922

Target: ALK|ROS1

Summary: ALK/ROS1 inhibitor,potent and selective

insoluble in H2O; ≥20.3 mg/mL
B5859 Entrectinib

Target: Trk Receptors|ALK|ROS1

Summary: Orally active inhibitor of ALK kinase

≥28.05 mg/mL