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Signaling Pathways

Signaling Pathways

A8255 Sunitinib malate
2 Citation

Target: VEGFR

Summary: VEGFR/PDGFRβ/ KIT/ FLT3/RET/CSF-1R inhibitor

≥26.65 mg/mL
A2251 Tivozanib (AV-951)

Target: VEGFR

Summary: VEGFR inhibitor,potent and selective

≥22.75 mg/mL
A8325 Tivantinib (ARQ 197)
2 Citation

Target: MET

Summary: C-Met inhibitor,non-ATP-competitive

≥18.47 mg/mL
A8370 Axitinib (AG 013736)
1 Citation

Target: VEGFR|PDGFR|c-Kit

Summary: VEGFR1/ c-Kit inhibitor

insoluble in H2O; ≥19.3 mg/mL