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Signaling Pathways

Items 11-20 of 80

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  1. VX-765
    A8238 VX-765
     1 Citation
    Target: Caspases
    Summary: Caspase-1 inhibitor,potent and selective
      insoluble in H2O; ≥313 mg/mL
  2. CA-074 Me
    A8239 CA-074 Me
     7 Citation
    Target: Cathepsins
    Summary: Cathepsin B inhibitor
      insoluble in H2O; ≥19.88 mg/mL
  3. 17-DMAG (Alvespimycin) HCl
    A2213 17-DMAG (Alvespimycin) HCl
     1 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor
      ≥26.2 mg/mL
  4. Odanacatib (MK-0822)
    A2487 Odanacatib (MK-0822)
    Target: Cathepsins
    Summary: Cathepsin K,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥17.7 mg/mL
  5. Daclatasvir (BMS-790052)
    A5618 Daclatasvir (BMS-790052)
    Target: HCV Proteases
    Summary: HCV NS5A inhibitor
      ≥36.6 mg/mL
  6. BIBR-1048
    A8381 BIBR-1048
    Summary: Thrombin inhibitor
      ≥30 mg/mL
  7. Saxagliptin
    A8650 Saxagliptin
    Target: DPP-4
    Summary: Selective DPP4 inhibitor
  8. Z-IETD-FMK
    B3232 Z-IETD-FMK
     12 Citation
    Target: Caspases
    Summary: Caspase-8 inhibitor
      ≥32.73 mg/mL
  9. UAMC 00039 dihydrochloride
    B5780 UAMC 00039 dihydrochloride
    Target: Dipeptidyl-peptidase II
    Summary: dipeptidyl peptidase II (DPP-II) inhibitor
      ≥133.6 mg/mL
  10. Gedunin
    B7393 Gedunin
    Target: HSP90
    Summary: naturally occurring Hsp90 inhibitor
      Soluble in DMSO

Items 11-20 of 80

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  1. Caspase10item
  2. Aminopeptidase2item
  3. Calpains5item
  4. Cathepsin8item
  5. DPP-45item
  6. Elastase3item
  7. Gamma Secretase8item
  8. HCV Protease6item
  9. HSP13item
  10. HIV Integrase2item
  11. HIV Protease5item
  12. MMP7item
  13. Serine Protease2item
  14. Thrombin5item
  15. Other Proteases2item
Reversibility
  1. Reversible13item
  2. Irreversible7item
Target
  1. Caspases10item
  2. Proteasome1 item
  3. Cathepsins11item
  4. MMP6item
  5. Factor Xa2item
  6. Thymidylate Synthase1 item
  7. Aminopeptidases2item
  8. HSP9010item
  9. Notch1 item
  10. thrombin1 item
  11. Renin1 item
  12. HIV proteases1 item
  13. Pepsins1 item
  14. Calpains5item
  15. HCV Proteases3item
  16. Trypsins1 item
  17. Trypsin1 item
  18. Chymotrypsin1 item
  19. Kallikrein1 item
  20. Trypsinogen1 item
  21. HIV-1 gp1201 item
  22. HIV Integrases1 item
  23. Inward Rectifier Potassium (Kir) Channels1 item
  24. Papains1 item
  25. DPP-44item
  26. Nonstructural protein 5B (NS5B)1 item
  27. ADAMs1 item
  28. Dipeptidyl-peptidase II1 item
  29. HCV polymerase2item
  30. Elastases1 item
  31. NE1 item
Reported Experiments
  1. Animal Experiments70item
  2. Cell Experiments49item
Related Disease
  1. Acute Lung Injury1 item
  2. Acute Myeloid Leukemia1 item
  3. Breast Cancer11item
  4. Cancer31item
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  14. Inflammatory Diseases1 item
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  17. Melanoma7item
  18. Multiple Myeloma2item
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  21. Osteoporosis1 item
  22. Ovarian Cancer4item
  23. Pancreatic Cancer3item
  24. Prostate Cancer3item
  25. Psoriasis1 item
  26. Renal Cell Carcinoma1 item
  27. Rheumatoid Arthritis3item
  28. Squamous Cell Carcinoma1 item
  29. Type 2 Diabetes1 item