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Signaling Pathways

Signaling Pathways

A8226 TAK-632

Target: Raf

Summary: Pan-RAF inhibitor,potent and selective

≥27.75 mg/mL
A8254 SB 203580
9 Citation

Target: p38|PKB

Summary: P38 MAP kinase inhibitor

insoluble in H2O; ≥18.872 mg/mL
A1855 Bumetanide

Target: Na /K /Cl- Symporters (NKCCs)

Summary: NKCC cotransporter inhibitor

insoluble in H2O; ≥36.37 mg/mL
A5071 GDC-0879
1 Citation

Target: Raf

Summary: B-Raf inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
A1632 SB202190 (FHPI)
5 Citation

Target: p38

Summary: P38 MAPK inhibitor
A5566 LY2228820
1 Citation

Target: p38

Summary: P38 MAP kinase inhibitor

≥30.65 mg/mL
A5573 Pimasertib (AS-703026)

Target: MEK

Summary: MEK1/2 inhibitor

≥21.55 mg/mL
A5707 PD318088

Target: MEK

Summary: Allosteric MEK1/2 inhibitor, non-ATP competitive

≥28.05 mg/mL
A5801 BIX 02189

Target: MEK|ERK

Summary: Selective MEK5 inhibitor

≥22.05 mg/mL
A5803 BIX 02188

Target: MEK

Summary: MEK5 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL