Search results for: 'research area jak stat signaling stat'
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BA8272 FolipastatinSummary: Folipastatin is a potent inhibitor. - BA8287 AlicapistatSummary: Alicapistat (ABT-957) is an orally active selective inhibitor of human calcium-activated neutral protease (and...
- BA8293 DazcapistatSummary: Dazcapistat is a potent calcineurin inhibitor.
- BA8336 PatamostatSummary: Patamostat (E-3123) is a potent protease inhibitor.
- BA8361 IrosustatSummary: Irosustat is a potent steroid sulfate esterase inhibitor.
- BA8399 TigulixostatSummary: Tigulixostat (LC350189) is a non-purine selective xanthine oxidase inhibitor with oral activity.
- BA8438 LanabecestatSummary: Lanabecestat (AZD3293) is an orally active, blood-brain barrier-crossing inhibitor.
- BA8440 AtabecestatSummary: Atabecestat (JNJ-54861911) is a potent brain-permeable and orally active beta-site amyloid precursor protein cleaving enzyme 1 inhibitor that potently reduces reduced Aβ protein expression in cerebrospinal fluid.
- BA8442 ElenbecestatSummary: Elenbecestat (E2609) is a highly potent, orally active, CNS permeable inhibitor.
- BA8443 UmibecestatSummary: Umibecestat (CNP520) is a β-site amyloid precursor protein cleavage enzyme-1 inhibitor with values of 11 nM and 10 nM in human BACE-1 and murine BACE-1, respectively.