Search results for: 'research area jak stat signaling stat'
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BA4139 CrebinostatSummary: Crebinostat is a potent inhibitor. - BA4141 RemetinostatSummary: Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase.
- BA8399 TigulixostatSummary: Tigulixostat (LC350189) is a non-purine selective xanthine oxidase inhibitor with oral activity.
- BA8438 LanabecestatSummary: Lanabecestat (AZD3293) is an orally active, blood-brain barrier-crossing inhibitor.
- BA8440 AtabecestatSummary: Atabecestat (JNJ-54861911) is a potent brain-permeable and orally active beta-site amyloid precursor protein cleaving enzyme 1 inhibitor that potently reduces reduced Aβ protein expression in cerebrospinal fluid.
- BA8442 ElenbecestatSummary: Elenbecestat (E2609) is a highly potent, orally active, CNS permeable inhibitor.
- BA8443 UmibecestatSummary: Umibecestat (CNP520) is a β-site amyloid precursor protein cleavage enzyme-1 inhibitor with values of 11 nM and 10 nM in human BACE-1 and murine BACE-1, respectively.
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BA8492 IbiglustatSummary: Ibiglustat (Venglustat) is an orally active, blood-brain barrier-crossing inhibitor of glucose ceramide synthetase. - BA8493 SinbaglustatSummary: Sinbaglustat (OGT2378) is a dual inhibitor of glucose ceramide synthetase and non-lysosomal glucose ceramidase.
- BA8585 UtreloxastatSummary: A compound for use in the study of diseases including alpha-synucleinopathies, tauopathies, ALS, traumatic brain injury, and ischemia-reperfusion related injury.