Search results for: 'hg6 64 1'
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BA6166 VipoglanstatSummary: Vipoglanstat (BI1029539), formamide, is a potent, selective, nonpeptide human prostaglandin E synthase 1 small molecule inhibitor with oral activity. -
A9087 alpha-SpinasterolSummary: α-Spinasterol is an orally taken antagonist of transient receptor potential vanilloid 1 ( TRPV1), and it's also an inhibitor of COX-1 and COX-2. - BA1909 GPI-1046Summary: GPI-1046, an immunoaffinity ligand without antibiotic effects, reduces ethanol intake by upregulating glutamate transporter protein 1 in the PFC and NAc core.
- BA8179 Enpp-1-IN-2Summary: Enpp-1-IN-2 is a potent (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with values of 0.26, 0.48, and 2.0 μM as determined by TG-mAMP, pNP-TMP, and ATP methods, respectively.
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P1131 Recombinant Human IL-20Summary: Human Interleukin-20 (IL-20) is encoded by the IL20 gene located on the chromosome 1 and belongs to the IL-10 family that including IL-10, IL-19, IL-22, IL-24, and IL-26. - BA8353 CAY10566Summary: CAY10566 is a potent, bio-orally available, selective inhibitor of stearoyl coenzyme A desaturase 1 at 4.5 and 26 nM in mouse and human enzyme assays, respectively.
- BA5455 BMS-986278Summary: BMS-986278 is a potent and orally active hemophosphatidic acid receptor 1 antagonist with values of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively.
- BA6642 GSK-5498ASummary: GSK-5498A is a selective calcium release-activated calcium channel inhibitor (1 μM).GSK-5498A inhibits mast cell mediator release and T cell pro-inflammatory cytokine release.
- BA4450 HWL-088Summary: HWL-088 is a potent, orally active free fatty acid receptor 1 agonist (at 18.9 nM) with moderate activity (at 570.9 nM).
- BA9221 H3B-5942Summary: H3B-5942 is a selective, irreversible, orally available covalent antagonist capable of targeting Cys530 and inactivating wild-type and mutant with values of 1 nM and 0.41 nM, respectively.