Caspase-7, human recombinant protein
Catalog No.
E1007
Caspase-7, expressed in E. coli, suitable for cell culture.
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Caspase-7 (also called Mch3, ICE-LAP3, CMH-1) belongs the caspase-family of cysteine proteases. Like other caspases, caspase-7 also exists as an inactive proenzyme in cells. Sequential activation of caspases plays a key role in the execution-phase of cell apoptosis. Caspases undergo proteolytic processing as inactive proenzymes by upstream caspases (caspase-8, -9) at conserved aspartic residues to produce two subunits, large one and small one. The two subunits dimerize to form the active enzyme in the form of a heterotetramer. Active caspase-7 has been shown involving in the proteolysis of poly ADP-ribose polymerase (PARP). PARP is involved in DNA repair and genomic maintenance. The precursor of this caspase is cleaved by caspase 10, caspase 3 and caspase 9. The recombinant active human caspase-7 was expressed in E. Coli.
| Gene ID: | 840 | Accession #: | P55210 |
| Alternate Names: | Active Human Caspase-7, Active Caspase-7, Caspase-7 Enzyme, Recombinant caspase-7, human caspase-7, human caspases, active caspases. | ||
| Source: | Escherichia Coli. | M.Wt: | N/A |
| Appearance: | Lyophilized powder | Storage: | Store at -70℃ |
| Formulation: | Lyophilized powder | ||
| Solubility: | Reconstitute to 1 unit per μl in PBS containing 15% glycerol. | ||
| Shipping Condition: | Gel pack. | Handling: | Centrifuge the vial prior to opening. |
| Usage: | For Research Use Only! Not to be used in humans. | ||
Quality Control & DataSheet
- View current batch:
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Purity: ≥90%, by SDS-PAGE.
Endotoxin Level:N/A