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Caspase-7, human recombinant protein

Catalog No.
E1007
Caspase-7, expressed in E. coli, suitable for cell culture.
Grouped product items
SizePriceStock Qty
25 units
$221.00
Ship with 10-15 days
100 units
$384.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

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Background

Caspase-7 (also called Mch3, ICE-LAP3, CMH-1) belongs the caspase-family of cysteine proteases. Like other caspases, caspase-7 also exists as an inactive proenzyme in cells. Sequential activation of caspases plays a key role in the execution-phase of cell apoptosis. Caspases undergo proteolytic processing as inactive proenzymes by upstream caspases (caspase-8, -9) at conserved aspartic residues to produce two subunits, large one and small one. The two subunits dimerize to form the active enzyme in the form of a heterotetramer. Active caspase-7 has been shown involving in the proteolysis of poly ADP-ribose polymerase (PARP). PARP is involved in DNA repair and genomic maintenance. The precursor of this caspase is cleaved by caspase 10, caspase 3 and caspase 9. The recombinant active human caspase-7 was expressed in E. Coli.

Description

Gene ID: 840 Accession #: P55210
Alternate Names:Active Human Caspase-7, Active Caspase-7, Caspase-7 Enzyme, Recombinant caspase-7, human caspase-7, human caspases, active caspases.
Source: Escherichia Coli. M.Wt: N/A
Appearance: Lyophilized powder Storage: Store at -70℃
Formulation:Lyophilized powder
Solubility:Reconstitute to 1 unit per μl in PBS containing 15% glycerol.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥90%, by SDS-PAGE.
    Endotoxin Level:N/A