Signaling pathways
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BA2321 MertansineSummary: Mertansine (DM1) is an inhibitor and an antibody-conjugatable medetomidine alkaloid used to overcome the systemic toxicity associated with medetomidine and to enhance tumor-specific delivery. -
BA2323 DM4Summary: DM4 is an anti-microtubule protein agent that inhibits cell division. -
BA2329 CC-885-CH2-PEG1-NH-CH3Summary: CC-885-CH2-PEG1-NH-CH3 is a new degradant. -
BA2330 PF-06380101Summary: PF-06380101 (Aur0101), a microtubule inhibitor. -
BA2333 T01-1Summary: T01-1 is an anticancer agent (camptothecin derivative). -
BA2334 MMAF-OMeSummary: MMAF-Ome is a tubulin inhibitor, a toxic molecule belonging to the ADC, and is able to inhibit four tumor cells, MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji(5T4). -
BA2335 DocetaxalSummary: Docetaxal (10-Acetyldocetaxel) is an analog. -
BA2336 FL118-14-PropanolSummary: FL118-14-Propanol is a FL118 derivative. -
BA2337 SC209Summary: SC209 is a cytotoxin that is used to synthesize anti-body-activated molecule-coupled ADCs. -
BA2338 Fmoc-MMAESummary: Fmoc-MMAE is the protecting group conjugated to MMAE.
