Signaling pathways
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BA2182 TigolanerSummary: Tigolaner is an antagonist and modulates chloride channels. - BA2196 NiranthinSummary: Niranthin is a lignan with a wide range of pharmacological activities.
- BA2199 TectolSummary: Tectol showed significant inhibitory effects on human leukemia cell lines HL60 and CEM.
- BA2201 HomobuteinSummary: Homobutein is a natural chalcone (which can be found in many medicinal plants, fruits, vegetables, spices, and nuts) and a potent dual inhibitor of HDACs/NF-κB with values of 190 and 38 μM, respectively.
- BA2202 PirimicarbSummary: Pirimicarb is a fast-acting, selective carbamate insecticide for a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables.
- BA2207 DHODH-IN-4Summary: DHODH-IN-4 is an inhibitor of human and dihydroorotic acid dehydrogenase with values of 4 μM and 0.18 μM for PfDHODH and HsDHODH, respectively.
- BA2208 IsogarcinolSummary: Isogarcinol (Cambogin) is an effective.
- BA2213 DHODH-IN-8Summary: DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotic acid dehydrogenase at 0.13 μM and 47.4 μM, respectively, and 0.016 μM and 5.6 μM, respectively.
- BA2215 PfDHODH-IN-1Summary: PfDHODH-IN-1 is an analog of the active metabolite of Leflunomide.
- BA2217 CevadineSummary: Cevadine is a voltage-sensitive sodium channel agonist.