Anti-infection
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BA2177 WarangaloneSummary: Warangalone is an anti-malarial compound that inhibits the growth of (chloroquine-sensitive) and (chloroquine-resistant) parasites with values of 4.8 μg/mL and 3.7 μg/mL, respectively. - BA2178 ArtefenomelSummary: Artefenomel (OZ439) is an orally active, synthetic anti-malarial compound containing an artemisinin pharmacophore with an artemisinin-like mechanism of action.
- BA2179 SR9186Summary: SR9186 (ML368) is a potent inhibitor.
- BA2180 ThiaclopridSummary: Thiacloprid is a chloronicotinic insecticide used primarily to control aphids in orchards and vegetables.
- BA2182 TigolanerSummary: Tigolaner is an antagonist and modulates chloride channels.
- BA2196 NiranthinSummary: Niranthin is a lignan with a wide range of pharmacological activities.
- BA2199 TectolSummary: Tectol showed significant inhibitory effects on human leukemia cell lines HL60 and CEM.
- BA2201 HomobuteinSummary: Homobutein is a natural chalcone (which can be found in many medicinal plants, fruits, vegetables, spices, and nuts) and a potent dual inhibitor of HDACs/NF-κB with values of 190 and 38 μM, respectively.
- BA2202 PirimicarbSummary: Pirimicarb is a fast-acting, selective carbamate insecticide for a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables.
- BA2207 DHODH-IN-4Summary: DHODH-IN-4 is an inhibitor of human and dihydroorotic acid dehydrogenase with values of 4 μM and 0.18 μM for PfDHODH and HsDHODH, respectively.