DiscoveryProbe™ TGF-beta/Smad Compound Library
Catalog No.
L1045
A unique collection of 88 TGF-beta/Smad inhibitors for TGF-beta/Smad signaling pathway research.
Featured Products
| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
| A1670 | Enzastaurin (LY317615) | PKC beta inhibitor,potent and selective | PKC | 170364-57-5 | CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7 |
| A1805 | Imatinib Mesylate (STI571) | Abl/c-kit/PDGFR inhibitor | Bcr-Abl | 220127-57-1 | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O |
| A2133 | Saracatinib (AZD0530) | Src/Abl inhibitor,potent and selective | Bcr-Abl | 379231-04-6 | CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6 |
| A3008 | Y-27632 dihydrochloride | ROCK1 inhibitor | ROCK | 146986-50-7;129830-38-2 | CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N |
| A5602 | SB525334 | (TGF-beta1) receptor inhibitor | TGF-βR1(ALK5) | 356559-20-1 | CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=NC=CN=C4C=C3 |
| A8249 | SB 431542 | ALK inhibitor | TGF-βR1(ALK5) | 301836-41-9 | C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
| A8342 | GF 109203X | Protein kinase C,MLCK,PKG and PKA inhibitor | PKC | 133052-90-1 | CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54 |
| A8348 | LY2157299 | TGF-βR1 inhibitor,potent and selective | TGF-βR1(ALK5) | 700874-72-2 | CC1=CC=CC(=N1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N |
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
| Form | Pre-dissolved DMSO solutions | Stability | Solution: -20°C for 12 months, -80°C for 24 months |
| Packaging | 96-well rack with Matrix 2D Barcoded ScrewTop Storage tubes (250 μL or 100 μL/well, 10 mM DMSO). 96-well DeepWell format with peelable foil seal and EVA cap (100 μL/well, 10 mM DMSO). |
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| Shipping Condition | Evaluation sample solution: ship with blue ice All other available size: ship with RT, or blue ice upon request |
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-- Available in stock with overnight delivery and free shipping over $500.
-- Cost-effective and competitive price to save your budget.
-- Potent, selective and cell-permeable in inhibiting or activating target molecules.
-- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
-- Detailed files describing potency, selectivity and applications etc.
-- Supported by published data from top peer-reviewed journals.
-- Guaranteed high quality with NMR and HPLC validation.
