3-Dehydrocholic acid

3-Oxocholic acid is an oxygen bile acid metabolite and belongs to the steroid compound class, mainly existing in the bile of mammals. As the main degradation product of Clostridium perfringens' bile metabolism in the intestinal tract, the generation of 3-Oxocholic acid depends on the modification of bile acid by the intestinal flora, reflecting the host-microbe metabolic interaction. In bile, 3-Oxocholic acid can participate in the regulation of emulsification and absorption of lipid substances by influencing the composition and polarity of the bile acid pool. Meanwhile, its steroid skeleton structure makes it possible for it to act as a ligand or signaling molecule, potentially participating in the regulatory network of nuclear receptors (such as fanitol X receptor FXR, progesterone X receptor PXR).