Ursocholic acid
Ursocholic acid is a primary bile acid present in the bile of mammals and can be converted into deoxycholic acid (Ursodeoxycholic acid, UDCA) under the action of the intestinal flora of mice. As a commonly used gallstone dissolving agent in clinical practice, its pharmacological effects are achieved through multiple mechanisms: in the liver, it protects liver cells through anti-apoptotic effects, and at the same time, it improves the state of bile stasis by means of anti-inflammatory, immunomodulatory and bile flow regulation functions; In addition, it can also coordinate mitochondrial function and cellular signaling pathways to maintain the integrity of liver cells. Especially in patients with chronic cholestasis, this substance can have a beneficial impact on bone health by regulating the balance of bile acid metabolism, and help alleviate the risk of bone diseases related to cholestasis. Its metabolic transformation and multi-target pharmacological activities make it a key molecule in the regulation of bile acid metabolism and the treatment of liver and gallbladder diseases.
| Physical Appearance | A solid |
| Storage | Store at -20°C for 3 years. |
| M.Wt | 408.57 |
| Cas No. | 2955-27-3 |
| Formula | C24H40O5 |
| Solubility | ≥52 mg/mL in DMSO; ≥53.1 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (R)-4-((3R,5S,7S,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
| Canonical SMILES | O=C(O)CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@@]21C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
