2'-F-dATP
Catalog No.
B7959
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2'-F-dATP is a fluorine-substituted nucleoside triphosphate analog derived from adenosine triphosphate (ATP), wherein fluorine replaces the hydroxyl group at the 2' position of the ribose sugar. This structural modification enhances molecular stability, allowing efficient incorporation into DNA by nucleic acid polymerases. Researchers utilize 2'-F-dATP to investigate enzyme substrate specificity, synthesize modified oligonucleotides, analyze nucleotide analog resistance mechanisms, probe nucleic acid structural dynamics, and facilitate advances in molecular diagnostics and antiviral drug development.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 509.2 (free acid) |
| Formula | C10H15N5O12P3F (free acid) |
| Synonyms | 2'-Fluoro-2'-deoxyadenosine-5'-Triphosphate |
| Chemical Name | (5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | NC1=NC=NC2=C1N=CN2C3C(F)C(O)C(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O3.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = ≥95% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
