ddATP
Catalog No.
B8136
Featured Products
ddATP (2',3'-dideoxyadenosine triphosphate) is a synthetic adenine nucleotide analog lacking hydroxyl groups at both the 2' and 3' positions of the ribose sugar. Due to the absence of the 3'-OH group, incorporation of ddATP into DNA by DNA polymerase prevents phosphodiester bond formation with subsequent nucleotides, resulting in chain termination. This property enables ddATP to competitively inhibit the incorporation of natural dATP during DNA synthesis. Thus, ddATP is widely utilized in molecular biology research, including Sanger sequencing, PCR termination assays, reverse transcriptase activity measurement, and studies investigating viral DNA replication mechanisms.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 475.1 (free acid) |
| Formula | C10H16N5O11P3 (free acid) |
| Synonyms | 2',3'-Dideoxyadenosine-5'-Triphosphate |
| Chemical Name | lithium (5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | NC1=NC=NC2=C1N=CN2C3CCC(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O3.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity ≥95% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
