ddCTP
ddCTP (2',3' -dideoxycytidine triphosphate) is a cytidine nucleotide derivative, which can be incorporated into DNA strands as a substrate for DNA polymerase. Due to the lack of 2' and 3' -hydroxyl groups on its sugar ring, when this compound is incorporated into the extended DNA strand, it can lead to the termination of strand extension and inhibit further DNA polymerization. ddCTP is often used in DNA sequencing, primer extension experiments and polymerase function tests to analyze and confirm the influence of nucleotide incorporation characteristics, DNA synthesis mechanisms and nucleotide modifications on DNA strand extension, and to assist in exploring the relationship between the specificity of DNA polymerase substrates and the function of active sites.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 451.1 (free acid) |
| Formula | C9H16N3O12P3 (free acid) |
| Synonyms | 2',3'-Dideoxycytidine-5'-Triphosphate, Zalcitabine triphosphate |
| Chemical Name | lithium (5-(4-amino-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | NC(C=CN1C2CCC(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)=NC1=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = ≥95% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
