ddTTP
Catalog No.
B8139
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ddTTP (2',3'-dideoxythymidine triphosphate) is a thymidine nucleotide analog utilized in molecular biology research. Structurally lacking hydroxyl groups at both the 2' and 3' ribose positions, it acts as a chain terminator during DNA synthesis catalyzed by DNA polymerases. Incorporation of ddTTP into a growing DNA strand prevents subsequent nucleotide addition, effectively terminating elongation. Due to this property, ddTTP is commonly employed in Sanger sequencing and primer extension assays to accurately determine DNA sequences and identify mutations.
| Physical Appearance | Solution |
| Storage | Store at -20°C or below |
| M.Wt | 466.1 (free acid) |
| Formula | C10H17N2O13P3 (free acid) |
| Synonyms | 2',3'-Dideoxythymidine-5'-Triphosphate |
| Chemical Name | lithium (5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate |
| SDF | Download SDF |
| Canonical SMILES | O=C(C(C)=CN1C2CCC(COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O2)NC1=O.[Li+].[Li+].[Li+].[Li+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = ≥95% by AX-HPLC
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
