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Fumonisin B1

In stock
Catalog No.
A4537
PP5/PP2Cα/PP2A/PP1γ2/PP2B inhibitor
Grouped product items
SizePriceStock Qty
1mg
$71.00
In stock
5mg
$319.00
In stock
10mg
$532.00
In stock

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Background

Mycotoxin produced by Fusarium moniliforme. Potently inhibits sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases (IC50 ~ 75 nM). Also inhibits protein phosphatases; IC50 values are 80, 300, 400, 500 and 3000 μM for PP5, PP2Cα, PP2A, PP1γ2 and PP2B respectively.

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt721.83
Cas No.116355-83-0
FormulaC34H59NO15
SolubilityLimited solubility, soluble in DMSO
Chemical Name2-[2-[19-amino-6-(3,4-dicarboxybutanoyloxy)-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
SDFDownload SDF
Canonical SMILESCCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

Fumonisin B1