Anti-Phospho-TrkB (Tyr817) Rabbit Monoclonal Antibody
Catalog No.
MA4570
Anti-Phospho-TrkB (Tyr817) Rabbit Monoclonal Antibody
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The family of Trk receptor tyrosine kinases consists of TrkA, TrkB and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. TrkA regulates proliferation and is important for development and maturation of the nervous system. Point mutations, deletions and chromosomal rearrangements (chimeras) cause ligand-independent receptor dimerization and activation of TrkA.
4915
NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 92 kDa; Observed MW: 140 kDa
Phosphorylated
IgG
Monoclonal Antibody
AP-6B7B6
Liquid
See label
Carrier Free
A synthesized peptide derived from human Phospho-TrkB (Y817)
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.