1-myristoylglycerophosphocholine

1-myristoylglycerophosphocholine (CAS No.: 20559-16-4) is a lysophospholipid belonging to the monoglycerophospholipid class, characterized by a phosphorylcholine head group linked to a glycerol backbone and commonly generated in plasma through lecithin:cholesterol acyltransferase-mediated lipid remodeling. As a bioactive lipid mediator, it participates in lipid signaling processes primarily through interaction with lysophospholipid-sensitive receptors and modulation of downstream signaling pathways that regulate enzyme activity and cellular responses. This compound has been widely utilized in biomedical research to investigate mechanisms of smooth muscle contraction and relaxation, owing to its observed antispasmodic properties, and is implicated in studies of inflammation, membrane dynamics, and receptor-mediated signal transduction. In vitro studies suggest that lysophospholipids of this class exert biological effects across nanomolar to micromolar concentration ranges, depending on the cellular context and assay system. In experimental settings, 1-myristoylglycerophosphocholine is commonly applied in cell-based assays and physiological models to explore lipid-mediated signaling and pharmacological modulation of muscle function, with concentrations or dosing regimens tailored to specific study designs and research objectives.