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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8314 Temsirolimus

Summary: MTOR inhibitor

≥51.5 mg/mL
A8315 NU7441 (KU-57788)
4 Citation

Target: PI3K|DNA-PK

Summary: DNA-PK inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.13 mg/mL
A8316 PD 0332991 (Palbociclib) HCl
15 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor

≥14.48 mg/mL
A8317 Fludarabine Phosphate (Fludara)
2 Citation

Target: STAT

Summary: Inhibits STAT1 activation and DNA synthesis

insoluble in EtOH; ≥17.6 mg/mL
A8318 PP242

Target: mTOR

Summary: MTOR inhibitor, selective and ATP-competitive
A8319 Dacomitinib (PF299804, PF299)

Target: ErbB

Summary: HER inhibitor

≥23.5 mg/mL
A8320 PF-00562271

Target: FAK|Pyk2

Summary: FAK/Pyk2 inhibitor,potent and ATP-competitive

insoluble in EtOH; insoluble in H2O; ≥11.1 mg/mL
A8321 Cisplatin
34 Citation

Summary: chemotherapeutic compound
A8322 Neratinib (HKI-272)
3 Citation

Target: EGFR

Summary: HER2/EGFR inhibitor,potent and irreversible

insoluble in H2O; ≥13.93 mg/mL
A8323 WP1130
1 Citation

Summary: Deubiquitinase (DUB) inhibitor, Cell permeable

≥38.4 mg/mL