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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8324 LDN-193189
8 Citation

Target: BMP and Other Activin Receptors

Summary: ALK inhibitor,potent and selective

insoluble in DMSO; insoluble in EtOH; insoluble in H2O
A8325 Tivantinib (ARQ 197)
2 Citation

Target: MET

Summary: C-Met inhibitor,non-ATP-competitive

≥18.47 mg/mL
A8326 AZD-5438
2 Citation

Target: Cyclin-Dependent Kinases

Summary: Potent CDK1/2/9 inhibitor

insoluble in H2O; ≥18.55 mg/mL
A8328 LDK378

Target: ALK

Summary: Potent ALK inhibitor

insoluble in H2O; ≥13.95 mg/mL
A8332 R788 disodium

Target: Syk

Summary: Syk inhibitor,ATP competitive and potent

≥62.4 mg/mL
A8333 Canagliflozin
1 Citation

Target: SGLT

Summary: SGLT2 inhibitor,potent and selective

≥22.25 mg/mL
A8334 Linsitinib
3 Citation

Summary: IGF1R/IR inhibitor,potent and novel

≥21.08 mg/mL
A8335 Palbociclib (PD0332991) Isethionate
1 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK4/6 inhibitor,highly selective

≥28.7 mg/mL
A8336 KU-60019
2 Citation

Target: ATM/ATR

Summary: ATM kinase inhibitor,potent and selective

≥27.4 mg/mL
A8337 CX-5461
2 Citation

Summary: Pol I-mediated rRNA synthesis inhibitor

insoluble in H2O; insoluble in EtOH; insoluble in DMSO