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Bioactive Compounds
Signaling Pathways

Signaling Pathways

A8302 Tenovin-6

Target: Sir2-like Family Deacetylases (Sirtuins)

Summary: SIRT inhibitor and p53 activator

≥22.75 mg/mL
A8303 GNF-5837

Target: Trk Receptors

Summary: Pan-Trk inhibitor

insoluble in EtOH; insoluble in H2O; ≥17 mg/mL
A8304 FR 180204

Target: ERK

Summary: ERK inhibitor

insoluble in H2O; ≥10.25 mg/mL
A8306 MOG (35-55)
1 Citation

Summary: Minor component of CNS myelin

≥32.25 mg/mL
A8307 Crenolanib (CP-868596)
1 Citation

Target: FLT3|PDGFR

Summary: PDGFR-β inhibitor,potent and selective

≥22.2 mg/mL
A8308 PH-797804
1 Citation

Summary: P38 MAP kinase inhibitor, potent and selective

≥23.85 mg/mL
A8309 Perifosine
1 Citation

Target: Akt

Summary: Akt inhibitor
A8310 PF-562271
1 Citation

Target: FAK|Pyk2

Summary: ATP-competitive FAK inhibitor, reversible

≥25.35 mg/mL
A8311 Maraviroc
2 Citation

Target: CCR

Summary: Selective CCR5 antagonist,antiretroviral agent

≥25.7 mg/mL
A8313 RAF265

Target: Raf|VEGFR

Summary: Multiple intracellular kinases inhibitor

≥25.9 mg/mL