Nigericin
Catalog No.
BA1112
Nigericin is an antibiotic.
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Nigericin is an antibiotic that acts as a K/H ion carrier and facilitates K/H exchange across mitochondrial membranes.Nigericin shows promising anticancer activity by lowering intracellular pH (pHi) and /pathway signaling.Nigericin induces cellular pyrokinesis via the /GSDMD pathway in TNBC.
| Storage | -20°C |
| M.Wt | 724.96 |
| Cas No. | 28380-24-7 |
| Formula | C40H68O11 |
| Solubility | ≥2.65 mg/mL in DMSO with gentle warming and ultrasonic; ≥53.1 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (R)-2-((2R,3S,6R)-6-(((2S,4R,5R,7R,9R,10R)-2-((2S,2'R,3'S,5R,5'R)-5'-((2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl)-2,3'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl)meth |
| SDF | Download SDF |
| Canonical SMILES | O=C(O)[C@H](C)[C@]1([H])O[C@](C[C@H]2O[C@@]3([C@H](C)C[C@]([C@]4([H])O[C@@]([C@@]5([H])[C@@H](C)C[C@@]([C@]6([H])[C@@H](C)C[C@@H](C)[C@@](CO)(O)O6)([H])O5)(C)CC4)(C)O3)[C@H](C)[C@H](OC)C2)([H])CC[C@@H]1C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
