Cysteamine HCl

Cysteamine HCl (156-57-0) is a small-molecule modulator designed to facilitate cystine export from lysosomes by lowering intracellular cystine levels. Cysteamine HCl exerts its biological activity primarily through cleaving cystine disulfide bonds and forming mixed disulfides, enabling cystine transport out of lysosomes. In in vitro assays, Cysteamine HCl demonstrates antioxidant activity, with reported IC50 values typically ranging between 30–80 µM depending on cell type and assay conditions. Cysteamine HCl is utilized in studies of cystinosis, lysosomal storage disorders, oxidative stress-related models, and cystine metabolic pathway analysis.