Lyso-Tracker Green
Lyso-Tracker Green is a fluorescent small-molecule probe designed specifically for labeling lysosomes in living cells. As a weakly basic fluorophore, it accumulates selectively in acidic cellular compartments, primarily lysosomes, due to protonation under low pH conditions. Unlike conventional dyes such as acridine orange or neutral red, Lyso-Tracker Green exhibits superior organellar selectivity and requires only nanomolar concentrations to produce robust fluorescent labeling. It is widely utilized in biomedical research for imaging lysosomal localization and analyzing cellular physiology in live-cell assays, but is not compatible with fixed-cell staining protocols.
Lyso-Tracker Green is a green-fluorescent probe that selectively labels Lysosomes of live cells. Lyso-Tracker Green consists of a fluorophore linked to a weak base that selectively tracks intracellular acidic organelles (for example, Lysosomes) of live cells. Unlike non-specific neutral red and acridine orange, Lyso-Tracker Green is highly selective for Lysosomes at nanomolar concentrations. Lyso-Tracker Green stains live cells well but is not suitable for fixed cells. This reagent is provided as a 1 mM solution in DMSO.
Physical Appearance | Liquid |
M.Wt | 398.7 |
Formula | C18H26BClF2N4O |
Ex/Em | 504/511 |
Synonyms | Lyso-Tracker Green DND-26 |
Storage | The product should be stored at -20°C away from light and moisture. |
Shipping Condition | Blue ice |
EXP Date | This product should be stored at -20°C away from light and moisture. Avoid repeated freeze/thaw cycles, stable for 6 months. |
Components | B8815-50 µL |
Lyso-Tracker Green | 50 µL (1 mM) |
This product should be stored at -20°C away from light and moisture. Avoid repeated freeze/thaw cycles, stable for 6 months. |