Metabolic Enzyme/Protease
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BA2830 BufotalinSummary: Bufotalin is a steroidal lactone isolated from VenenumBufonis with potent antitumor activity. - BA2820 HinokiflavoneSummary: Hinokiflavone, a novel modulator of splicing activity, is effective in vitro and in vivo.
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BA2815 MitoBloCK-6Summary: MitoBloCK-6 is a potent inhibitor. - BA2806 SC-43Summary: SC-43, a derivative of Sorafenib, is a potent agonist with oral activity.
- BA2801 3-HydroxykynurenineSummary: 3-Hydroxykynurenine, a tryptophan metabolite, is a potential endogenous neurotoxin with elevated expression levels in several neurodegenerative diseases.
- BA2798 TM5441Summary: TM5441, an orally bioavailable inhibitor of fibrinogen activator inhibitor-1, inhibited several cancer cell lines with values ranging from 13.9 to 51.1 μM and induced intrinsic cell death in several human cancer cells.
- BA2795 1G244Summary: 1G244 was a potent inhibitor at 12 nM and 84 nM, respectively, but did not inhibit DPPIV and DPPII.
- BA2783 BTdCPUSummary: BTdCPU is a heme-regulated inhibitory kinase activator that promotes phosphorylation and induces apoptosis in (Dex)-resistant cancer cells.
- BA2782 JX06Summary: JX06 is a potent, selective, covalent inhibitor.
- BA2778 POMHEXSummary: POMHEX is a racemic mixture of POM precursor active molecules that are cell-permeable and specific inhibitors of HEX.