Mycoplasma Removal Spray

Mycoplasmas are the smallest prokaryotic microorganism, only 0.1-0.3 μm in size. Due to their small size, mycoplasmas can penetrate rated filters (0.22~0.45 μm). Mycoplasma contamination remains a major problem in cell culture. Mycoplasmas can alter the DNA, RNA, and protein synthesis of culture cells, but they may not noticeably affect cell growth rates in many cases. Mycoplasma contamination in cell culture can occur from various sources, such as contaminated cells, consumables, the environment, etc. The environment is the most common reason. Therefore, it is important to perform regular mycoplasma removal in the cell culture environment.

The traditional method of removing mycoplasma in cell culture environments is mainly formaldehyde permanganate fumigation and alcohol wiping. Both methods are cumbersome and may have a toxic effect on the human body.

Mycoplasma Removal Spray is a safe, effective, and easy-to-use environmental mycoplasma removal reagent. This reagent contains a surfactant peptide extracted from the fermentation of Bacillus subtilis, which can selectively bind to the mycoplasma membrane and change the permeability of the mycoplasma membrane, thereby directly killing mycoplasma. At the same time, it cannot cross the cell membrane of eukaryotic cells, so it does not affect the cell.

This reagent is a ready-to-use scavenger, which can be sprayed directly on the area to be treated, and remove mycoplasma within 5-10 min. At the same time, this reagent uses water and ethanol as solvents, and does not contain toxic substances such as mercury, phenol and formaldehyde, which is safe and non-toxic, and will not damage the work surface.