MPP+ iodide
Catalog No.
C8601
MPP⁺ iodide is a toxic metabolite of MPTP and a high-affinity substrate of the serotonin transporter (SERT), used to induce Parkinsonian symptoms in dopaminergic neuron models.
Featured Products
MPP⁺ iodide (1-Methyl-4-phenylpyridinium iodide) is a neurotoxic metabolite of MPTP and a high-affinity substrate of the serotonin transporter (SERT). It selectively accumulates in dopaminergic neurons via the dopamine transporter (DAT), where it disrupts mitochondrial complex I and triggers cell death. This compound is widely used to induce Parkinson’s disease-like pathology in cellular and animal models, supporting studies on neurodegeneration, oxidative stress, and neuroprotection.
| Storage | Store at 4°C away from light. Powder: -20°C for 3 years. Liquid: -80°C for 1 year. |
| M.Wt | 297.14 |
| Cas No. | 36913-39-0 |
| Formula | C12H12IN |
| Synonyms | N-Methyl-4-Phenylpyridinium Iodide |
| Solubility | Soluble in DMSO |
| Chemical Name | 1-methyl-4-phenylpyridin-1-ium iodide |
| SDF | Download SDF |
| Canonical SMILES | C[N+]1=CC=C(C2=CC=CC=C2)C=C1.[I-] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |