Chlorin e6
Catalog No.
B8314
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Chlorin e6 (Ce6; CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research, with demonstrated anticancer activity when activated by laser irradiation. Upon irradiation, Ce6 generates reactive oxygen species, mediating cytotoxic effects and cellular apoptosis. In mouse models, intravenous administration of Ce6 (2.5–10 mg/kg) combined with irradiation (50–200 J/cm2) resulted in complete elimination of implanted fibrosarcomas. In clinical trials for bronchogenic superficial squamous cell carcinoma, Ce6-based PDT (40 mg/m2; 100 J/cm2) produced complete response rates up to 82.9%, underscoring its utility for cancer therapy studies.
| Storage | Store at -20°C |
| M.Wt | 596.67 |
| Cas No. | 19660-77-6 |
| Formula | C34H36N4O6 |
| Synonyms | Ce6 |
| Solubility | ≤30 mg/mL in DMSO |
| Chemical Name | (7S,8S)-3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-21H,23H-porphine-7-propanoic acid |
| SDF | Download SDF |
| Canonical SMILES | CC1=C2NC(/C(CC(O)=O)=C(N=C3/C=C4N/C(C(C=C)=C\4C)=C\C5=N/C(C(CC)=C5C)=C\2)/[C@@H](CCC(O)=O)[C@@H]3C)=C1C(O)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
