Natural Products


Natural products are compounds produced by living organisms—including animals, plants, and microorganisms—and include both structural components and secondary metabolites. Plants, in particular, are a major source, rich in bioactive constituents like flavonoids and alkaloids, which underpin the pharmacological effects of traditional Chinese medicine. While natural products are primarily obtained through chemical isolation, they can also be prepared by semi-synthetic or total synthesis methods. Their complex structures pose significant challenges for organic chemists.
Natural products represent a core source of lead compounds for innovative drug discovery, providing bioactive templates that facilitate biochemical research, the identification of novel therapeutic targets, the development of new therapies, and the elucidation of underlying mechanisms. In addition, natural products are widely applied in the fields of food, cosmetics, and health supplements, where their antioxidant, anti-inflammatory, and other bioactivities support research into related diseases.
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N2857 (-)-IsocorypalmineSummary: A natural isoquinoline alkaloid isolated from the crude alkaloid of Corydalis yanhusuo -
N2858 (-)-Hydroxycitric acid lactoneSummary: An effective ATP-citrate lyase inhibitor -
N2859 α-TocopherylquinoneSummary: A quinone compound isolated from natural sources such as Phaeodactylum tricornutum -
C8598 TPMPA (hydrate)Summary: TPMPA is a selective competitive antagonist for GABAA-ρ (also known as GABAC) receptors, particularly showing selectivity for the ρ1 subtype over ρ2. -
C8647 Angeloylgomisin HSummary: Angeloylgomisin H is a lignan compound extracted from Schisandra rubriflora, which enhances insulin-stimulated glucose uptake by activating PPAR-γ. -
N2860 (+)-MagnoflorineSummary: An aporphine alkaloid isolated from Acorus calamus -
C8658 5-O-Caffeoylquinic acid methyl esterSummary: A chlorogenic acid derivative -
C8661 4-Methoxychalcone-1Summary: A PPARγ agonist -
N2861 Maduramicin (ammonium salt)Summary: A polyether ionophore antibiotic -
N2862 Diffractaic acidSummary: A lichen metabolite with diverse biological activities

