Natural Products


Natural products are compounds produced by living organisms—including animals, plants, and microorganisms—and include both structural components and secondary metabolites. Plants, in particular, are a major source, rich in bioactive constituents like flavonoids and alkaloids, which underpin the pharmacological effects of traditional Chinese medicine. While natural products are primarily obtained through chemical isolation, they can also be prepared by semi-synthetic or total synthesis methods. Their complex structures pose significant challenges for organic chemists.
Natural products represent a core source of lead compounds for innovative drug discovery, providing bioactive templates that facilitate biochemical research, the identification of novel therapeutic targets, the development of new therapies, and the elucidation of underlying mechanisms. In addition, natural products are widely applied in the fields of food, cosmetics, and health supplements, where their antioxidant, anti-inflammatory, and other bioactivities support research into related diseases.
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N2895 IsoquercitrinSummary: A natural polyphenolic flavonoid inhibitor of the Wnt/β-catenin pathway. -
N2896 Sodium aescinateSummary: A triterpenoid saponin compound that regulates the CARMA3/NF-κB signaling pathway. -
N2897 Levofloxacin hemihydrateSummary: A broad-spectrum third-generation fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV. -
N2898 Hydrocortisone butyrate1 CitationSummary: A potent synthetic glucocorticoid receptor (GR) agonist. -
N2899 9-DeoxyforskolinSummary: A forskolin-like diterpenoid compound derived from hairy root cultures of Coleus forskohlii. -
N2900 Ginsenoside Rh4Summary: A rare saponin compound derived from Panax notoginseng. -
N2901 Ginsenoside Rk3Summary: A saponin NF-κB transcriptional activity inhibitor derived from ginseng root. -
N2902 Ginsenoside Rk2Summary: A dammarane-type saponin compound extracted from processed ginseng (Panax ginseng). -
BA6355 KhellinSummary: A natural furochromone epidermal growth factor receptor (EGFR) inhibitor. -
BA7429 MaltoseSummary: A reducing disaccharide composed of two glucose molecules linked by an α(1-4) bond.

