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Bioactive Compounds

Bioactive Compounds

A2960 Loratadine

Target: Histamine H1 Receptors

Summary: Peripheral HH1R antagonist

insoluble in H2O; ≥19.14 mg/mL
A2307 PHA-665752
1 Citation

Target: c-MET

Summary: C-Met inhibitor,potent and ATP-competitive
A2942 Masitinib (AB1010)
3 Citation

Target: PDGFR|c-Kit|Lyn

Summary: Tyrosine kinase inhibitor, potent and selective

≥24.95 mg/mL
A2036 Doripenem Hydrate

Target: Antibiotic

Summary: Injectable antibiotic,ultra-broad spectrum

insoluble in EtOH; ≥10.96 mg/mL
A1389 WZ4002

Summary: Mutant-selective EGFR inhibitor(L858R,T790M), irreversible and potent

≥24.7 mg/mL
A1980 SNS-032 (BMS-387032)
3 Citation

Target: Cyclin-Dependent Kinases

Summary: CDK inhibitor

insoluble in H2O; ≥19.05 mg/mL
A1882 Cediranib (AZD217)

Target: VEGFR

Summary: VEGFR inhibitor receptor,highly potent

≥22.52 mg/mL
A1736 PA-824
2 Citation

Summary: Anti-tuberculosis drug

insoluble in EtOH; insoluble in H2O; ≥17.85 mg/mL
A1630 Epothilone B (EPO906, Patupilone)

Target: Microtubules/Tubulins

Summary: Microtubule stabilizing macrolide

≥25.4 mg/mL
A2487 Odanacatib (MK-0822)

Target: Cathepsins

Summary: Cathepsin K,potent and selective

insoluble in EtOH; insoluble in H2O; ≥17.7 mg/mL