Betulinic acid
Catalog No.
A3237
Anti-HIV and antitumor compound,pentacyclic triterpenoid
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Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources, exhibiting pharmacological properties relevant to oncology and infectious diseases research. It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling. Additionally, betulinic acid functions as an agonist for the bile acid receptor TGR5, demonstrating activity with an EC50 of approximately 1.04 μM. Due to its apoptotic effects and antiviral properties, betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 456.7 |
| Cas No. | 472-15-1 |
| Formula | C30H48O3 |
| Synonyms | Lupatic acid,Betulic acid,Mairin,NSC113090,NSC-113090 |
| Solubility | ≥22.85 mg/mL in DMSO; insoluble in H2O; ≥9.62 mg/mL in EtOH with gentle warming and ultrasonic |
| Chemical Name | (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid |
| SDF | Download SDF |
| Canonical SMILES | [H][C@]12[C@@](CC[C@H]2C(C)=C)(C(O)=O)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@@]31[H] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
