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Betulinic acid

Catalog No.
A3237
Anti-HIV and antitumor compound,pentacyclic triterpenoid
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$61.00
In stock
100mg
$55.00
In stock
200mg
$94.00
In stock
500mg
$198.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources, exhibiting pharmacological properties relevant to oncology and infectious diseases research. It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling. Additionally, betulinic acid functions as an agonist for the bile acid receptor TGR5, demonstrating activity with an EC50 of approximately 1.04 μM. Due to its apoptotic effects and antiviral properties, betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies.

Product Citation

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt456.7
Cas No.472-15-1
FormulaC30H48O3
SynonymsLupatic acid,Betulic acid,Mairin,NSC113090,NSC-113090
Solubility≥22.85 mg/mL in DMSO; insoluble in H2O; ≥9.62 mg/mL in EtOH with gentle warming and ultrasonic
Chemical Name(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
SDFDownload SDF
Canonical SMILES[H][C@]12[C@@](CC[C@H]2C(C)=C)(C(O)=O)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@@]31[H]
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control