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Bioactive Compounds

Bioactive Compounds

A4322 Clarithromycin

Target: Cytochrome P450 (CYP450)

Summary: CYP3A inhibitor, potent

≥31.2 mg/mL
A4333 CPI-613

6 Citation

Target: Pyruvate dehydrogenases (PDH)

Summary: PDH/α-KGDH inhibitor

insoluble in H2O; ≥19.45 mg/mL
A4335 Mildronate

Target: Hydroxylases|carnitine reabsorption

Summary: GBB hydroxylase inhibitor
A4353 Pyrimethamine

Summary: DHFR inhibitor

insoluble in H2O; ≥10 mg/mL
A4360 Topiramate

Summary: GluR5 receptor antagonist,anticonvulsant

≥16.95 mg/mL
A4367 Atorvastatin Calcium

Target: HMG-CoA Reductases

Summary: HMG-CoA reductase inhibitor

≥57.75 mg/mL
A4374 PF-3845

1 Citation

Target: FAAH

Summary: FAAH ihibitor,highly potent and selective

≥55.6 mg/mL
A4378 Torcetrapib

Summary: CETP inhibitor

≥22.4 mg/mL
A4382 A922500

Target: DGAT

Summary: DGAT-1 inhibitor

≥21.25 mg/mL
A3108 Clascoterone

Summary: Androgen antagonist

≥52.2 mg/mL