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Pyrimethamine

Catalog No.
A4353
DHFR inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$66.00
In stock
100mg
$63.00
In stock
500mg
$133.00
In stock

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Background

Pyrimethamine is a dihydrofolate reductase(DHFR) inhibitor with an IC50 of 15.4 nM.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt248.71
Cas No.58-14-0
FormulaC12H13ClN4
Solubility≥10 mg/mL in DMSO with gentle warming, ≥5.23 mg/mL in EtOH with ultrasonic,insoluble in H2O
Chemical Name5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
SDFDownload SDF
Canonical SMILESCCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Chemical structure

Pyrimethamine