ARS-1620
Catalog No.
BA5766
A covalent inhibitor targeting the KRAS G12C mutant that blocks RAS signaling
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ARS-1620 is a blocking allosteric and selective inhibitor with ideal pharmacokinetics.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 430.84 |
| Cas No. | 1698055-85-4 |
| Formula | C21H17ClF2N4O2 |
| Solubility | ≥51.3 mg/mL in DMSO; ≥51.3 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one |
| Canonical SMILES | C=CC(N1CCN(C2=C3C=C(Cl)[C@]([C@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
