Anti-Bax (2B12) Mouse Monoclonal Antibody
Catalog No.
MA1415
Anti-Bax (2B12) Mouse Monoclonal Antibody
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Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
581
Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
Mouse
Human, Monkey
Unconjugated
Calculated MW: 21 kDa; Observed MW: 21 kDa
Unmodified
IgG2a
Monoclonal Antibody
AP-2F8C8
Liquid
See label
Carrier Not Free
Purified recombinant human Bax protein fragments expressed in E.coli
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.