Zerumbone
Catalog No.
B8317
Zerumbone
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Zerumbone is a sesquiterpene isolated from in Zingiber zerumbet Smith (wild ginger),which exhibits antitumor activity[1].Zerumbone is a TRAIL-induced apoptosis potentiator. It potentiates TRAIL-induced apoptosis through the up-regulation of DR4 and DR5 expression and the down-regulation of cFLIP. Zerumbone has very little or no cytotoxic effect on the normal human endothelial cells and dermal fibroblasts.
References:
[1]Kamalidehghan B, Ahmadipour F, Noordin M I. DNA Fragmentation Is Not Associated with Apoptosis in Zerumbone-induced HepG2 Cells[J]. Iranian Biomedical Journal, 2012, 16(4):226.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 218.33 |
| Cas No. | 471-05-6 |
| Formula | C15H22O |
| Solubility | insoluble in H2O; ≥44.4 mg/mL in EtOH; ≥81.4 mg/mL in DMSO |
| Chemical Name | (2Z,6E,10E)-2,6,9,9-tetramethylcycloundeca-2,6,10-trienone |
| SDF | Download SDF |
| Canonical SMILES | C/C1=C/CC/C(C)=C/CC(C)(C)/C=C/C1=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
