Vidarabine
Catalog No.
B2062
antiviral drug for herpes viruses
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Vidarabine (CAS: 5536-17-4) is an antiviral nucleoside analog widely studied for inhibiting replication of herpes simplex virus (HSV) and varicella-zoster virus (VZV). Structurally, vidarabine is an adenine arabinoside analog that interferes with viral DNA synthesis via competitive inhibition of viral DNA polymerase, resulting in chain termination. In vitro studies demonstrate antiviral activity against HSV type 1 and type 2 with IC50 values typically ranging approximately from 0.1 to 1.0 μM, depending on experimental conditions and viral strains. Vidarabine is commonly used in biomedical laboratories for investigating viral replication mechanisms, screening for antiviral candidates, and elucidating nucleoside analog resistance patterns.
| Storage | Store at -20°C |
| M.Wt | 267.24 |
| Cas No. | 5536-17-4 |
| Formula | C10H13N5O4 |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥12.35 mg/mL in DMSO |
| Chemical Name | (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
| SDF | Download SDF |
| Canonical SMILES | Nc1c2nc[n]([C@@H]([C@H]3O)O[C@H](CO)[C@H]3O)c2ncn1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
