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Ursodeoxycholic Acid (sodium salt)

Catalog No.
C4990
A naturally occurring secondary bile acid that modulates TGR5 (GPCR19)- and farnesoid X receptor (FXR)-related signaling pathways.
Grouped product items
Size Price Stock Qty
500mg
$95.00
In stock
1g
$171.00
In stock
5g
$599.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Ursodeoxycholic Acid (sodium salt) (CAS No.: 2898-95-5) is a naturally occurring secondary bile acid formed from cholic acid through microbial transformation in the intestine. It plays a key regulatory role in maintaining intestinal barrier integrity and lipid metabolism. As a signaling molecule, Ursodeoxycholic Acid sodium interacts with bile acid-activated receptors, especially G protein-coupled bile acid receptor 5 (TGR5, GPCR19) and farnesoid X receptor (FXR), influencing multiple signaling pathways related to liver and gastrointestinal research. In vitro, its activity is typically observed in the nanomolar to micromolar range. In research, it is commonly used in cell and animal models to explore its ability to modulate bile acid pathways and its potential role in liver and gastrointestinal research. The concentrations or doses used in such experiments generally depend on the specific research objectives and experimental design. With its biological functions and interactions with receptor targets, Ursodeoxycholic Acid sodium is a valuable tool for studying bile acid signaling and related metabolic pathways.

Chemical Properties

Physical AppearanceA crystalline solid
Storage-20°C
M.Wt414.55
Cas No.2898-95-5
FormulaC24H39NaO4
SynonymsUrsodeoxycholate sodium; Ursodiol sodium; UCDA sodium
Solubility≥156.2 mg/mL in DMSO; ≥19.9 mg/mL in EtOH; ≥45.1 mg/mL in H2O
Chemical Namesodium (R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Canonical SMILES[O-]C(CC[C@H]([C@]1(CC[C@]2([C@@]3([C@H](C[C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)O)[H])O)[H])[H])[H])C)=O.[Na+]
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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