Uridine-5'-O-(3-thiotriphosphate) (sodium salt)
Catalog No.
A9081
A hydrolysis-resistant derivative of UTP and an agonist of the purinergic P2Y2 receptor.
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Uridine-5'-O-(3-thiotriphosphate) (UTP-γ-S) is a hydrolysis-resistant derivative of UTP and an agonist of the purinergic P2Y2 receptor. It induces inositol phosphate production in 1321N1 astrocytoma cells expressing the human P2Y2 receptor (EC₅₀ = 240 nM) and induces chloride secretion in a concentration-dependent manner in primary nasal epithelial cells from cystic fibrosis patients. Additionally, UTP-γ-S triggers vasoconstriction in isolated human coronary arteries (EC₅₀ = 25.1 μM).
| Storage | Store at -20°C |
| M.Wt | 588.13 |
| Formula | C9H11N2Na4O14P3S |
| Synonyms | UTP-γ-S |
| Solubility | Soluble in DMSO |
| SDF | Download SDF |
| Canonical SMILES | O=C(N([C@@H]1O[C@H](COP(OP(OP([O-])([S-])=O)([O-])=O)([O-])=O)[C@@H](O)[C@H]1O)C=C2)N([H])C2=O.[Na+].[Na+].[Na+].[Na+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
