Uridine-5'-diphosphoglucuronic Acid (sodium salt)

Uridine-5'-diphosphoglucuronic Acid (sodium salt) (CAS No.: 63700-19-6) is a nucleotide sugar derivative that functions as a central metabolic intermediate in glycoconjugate biosynthesis, serving as an essential precursor for the formation of glycosaminoglycans in mammalian systems, structural polysaccharides in plant cell walls, and capsule-associated glycoconjugates in bacteria. As a key donor substrate in glucuronidation and glycosylation reactions, it is utilized by glycosyltransferases and related enzymes to regulate the assembly and modification of complex carbohydrate structures, thereby influencing cellular signaling pathways, extracellular matrix organization, and detoxification processes. Emerging studies indicate that this compound may modulate enzyme activity and biochemical signaling networks associated with carbohydrate metabolism, although its effects are typically characterized in vitro at concentrations ranging from nanomolar to micromolar levels depending on assay conditions. Widely employed in biochemical and cell-based assays, Uridine-5'-diphosphoglucuronic Acid (sodium salt) is a valuable tool for investigating metabolic pathways, enzyme kinetics, and glycan-related biological functions, as well as for supporting target validation and mechanism-of-action studies in drug discovery; experimental concentrations and protocols vary according to specific model systems and research objectives.